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Safety of long-term intrathecal methotrexate in progressive forms of MS

BACKGROUND: There are few treatment options for multiple sclerosis (MS) patients with advanced disability [expanded disability status scale (EDSS) ⩾ 6.0]. In 2010, we reported initial results of using intrathecal methotrexate (ITMTX) in patients with progressive MS. We now report on long-term use of...

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Detalles Bibliográficos
Autores principales: Stark, James W., Josephs, Lena, Dulak, Deirdre, Clague, Madison, Sadiq, Saud A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6891004/
https://www.ncbi.nlm.nih.gov/pubmed/31832101
http://dx.doi.org/10.1177/1756286419892360