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Regulation of MT dynamics via direct binding of an Abl family kinase

Abl family kinases are essential regulators of cell shape and movement. Genetic studies revealed functional interactions between Abl kinases and microtubules (MTs), but the mechanism by which Abl family kinases regulate MTs remains unclear. Here, we report that Abl2 directly binds to MTs and regulat...

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Detalles Bibliográficos
Autores principales: Hu, Yuhan, Lyu, Wanqing, Lowery, Laura Anne, Koleske, Anthony J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6891085/
https://www.ncbi.nlm.nih.gov/pubmed/31699690
http://dx.doi.org/10.1083/jcb.201812144