Cargando…
Regulation of MT dynamics via direct binding of an Abl family kinase
Abl family kinases are essential regulators of cell shape and movement. Genetic studies revealed functional interactions between Abl kinases and microtubules (MTs), but the mechanism by which Abl family kinases regulate MTs remains unclear. Here, we report that Abl2 directly binds to MTs and regulat...
Autores principales: | Hu, Yuhan, Lyu, Wanqing, Lowery, Laura Anne, Koleske, Anthony J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6891085/ https://www.ncbi.nlm.nih.gov/pubmed/31699690 http://dx.doi.org/10.1083/jcb.201812144 |
Ejemplares similares
-
Platelet-derived growth factor receptor beta activates Abl2 via direct binding and phosphorylation
por: Wu, Kuanlin, et al.
Publicado: (2021) -
Abl2 is recruited to ventral actin waves through cytoskeletal interactions to promote lamellipodium extension
por: Zhang, Ke, et al.
Publicado: (2018) -
A Role for the Non-Receptor Tyrosine Kinase Abl2/Arg in Experimental Neuroinflammation
por: Jacobsen, Freja Aksel, et al.
Publicado: (2018) -
The Abl-related gene (Arg) requires its F-actin–microtubule cross-linking activity to regulate lamellipodial dynamics during fibroblast adhesion
por: Miller, Ann L., et al.
Publicado: (2004) -
Regulation of Actin Polymerization and Adhesion-Dependent Cell Edge Protrusion by the Abl-Related Gene (Arg) Tyrosine Kinase and N-WASp
por: Miller, Matthew M., et al.
Publicado: (2010)