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CDK1-mediated CENP-C phosphorylation modulates CENP-A binding and mitotic kinetochore localization
The kinetochore is essential for faithful chromosome segregation during mitosis. To form a functional kinetochore, constitutive centromere-associated network (CCAN) proteins are assembled on the centromere chromatin that contains the centromere-specific histone CENP-A. CENP-C, a CCAN protein, direct...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6891089/ https://www.ncbi.nlm.nih.gov/pubmed/31676716 http://dx.doi.org/10.1083/jcb.201907006 |