Cargando…

Delineating the contribution of Spc105-bound PP1 to spindle checkpoint silencing and kinetochore microtubule attachment regulation

Accurate chromosome segregation during cell division requires the spindle assembly checkpoint (SAC), which detects unattached kinetochores, and an error correction mechanism that destabilizes incorrect kinetochore–microtubule attachments. While the SAC and error correction are both regulated by prot...

Descripción completa

Detalles Bibliográficos
Autores principales: Roy, Babhrubahan, Verma, Vikash, Sim, Janice, Fontan, Adrienne, Joglekar, Ajit P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6891095/
https://www.ncbi.nlm.nih.gov/pubmed/31649151
http://dx.doi.org/10.1083/jcb.201810172