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Inverse pharmacology: Approaches and tools for introducing druggability into engineered proteins

A major feature of twenty-first century medical research is the development of therapeutic strategies that use ‘biologics’ (large molecules, usually engineered proteins) and living cells instead of, or as well as, the small molecules that were the basis of pharmacology in earlier eras. The high powe...

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Detalles Bibliográficos
Autores principales: Davies, Jamie A., Ireland, Sam, Harding, Simon, Sharman, Joanna L., Southan, Christopher, Dominguez-Monedero, Alazne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6891246/
https://www.ncbi.nlm.nih.gov/pubmed/31494210
http://dx.doi.org/10.1016/j.biotechadv.2019.107439