Iminosugars counteract the downregulation of the interferon γ receptor by dengue virus

The antiviral mechanism of action of iminosugars against many enveloped viruses is hypothesized to be a consequence of misfolding of viral N-linked glycoproteins through inhibition of host endoplasmic reticulum α-glucosidase enzymes. Iminosugar treatment of dengue virus (DENV) infection results in r...

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Detalles Bibliográficos
Autores principales: Miller, Joanna L., Hill, Michelle L., Brun, Juliane, Pountain, Andrew, Sayce, Andrew C., Zitzmann, Nicole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6891261/
https://www.ncbi.nlm.nih.gov/pubmed/31306674
http://dx.doi.org/10.1016/j.antiviral.2019.104551

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6891261/
https://www.ncbi.nlm.nih.gov/pubmed/31306674
http://dx.doi.org/10.1016/j.antiviral.2019.104551

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