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Iminosugars counteract the downregulation of the interferon γ receptor by dengue virus

The antiviral mechanism of action of iminosugars against many enveloped viruses is hypothesized to be a consequence of misfolding of viral N-linked glycoproteins through inhibition of host endoplasmic reticulum α-glucosidase enzymes. Iminosugar treatment of dengue virus (DENV) infection results in r...

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Detalles Bibliográficos
Autores principales:	Miller, Joanna L., Hill, Michelle L., Brun, Juliane, Pountain, Andrew, Sayce, Andrew C., Zitzmann, Nicole
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6891261/ https://www.ncbi.nlm.nih.gov/pubmed/31306674 http://dx.doi.org/10.1016/j.antiviral.2019.104551

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