Plocabulin Displays Strong Cytotoxic Activity in a Personalized Colon Cancer Patient-Derived 3D Organoid Assay

Plocabulin is a novel microtubule-disrupting antitumor agent of marine origin that is currently undergoing phase II clinical trials. Plocabulin has potent antiproliferative and antiangiogenic actions in carcinoma cell lines and has antitumor activity in xenografted mice. Here, we used three-dimensio...

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Detalles Bibliográficos
Autores principales: Costales-Carrera, Alba, Fernández-Barral, Asunción, Bustamante-Madrid, Pilar, Guerra, Laura, Cantero, Ramón, Barbáchano, Antonio, Muñoz, Alberto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6891270/
https://www.ncbi.nlm.nih.gov/pubmed/31752287
http://dx.doi.org/10.3390/md17110648

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6891270/
https://www.ncbi.nlm.nih.gov/pubmed/31752287
http://dx.doi.org/10.3390/md17110648

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