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Synthesis of Novel Farnesoid X Receptor Agonists and Validation of Their Efficacy in Activating Differentiation of Mouse Bone Marrow-Derived Mesenchymal Stem Cells into Osteoblasts

The modulators of farnesoid X receptor (FXR), a bile acid receptor, regulate various biological processes including bile acid metabolism, and are associated with the control of fatty liver and osteoporosis. Thus, the control of FXR activity and development of FXR modulators are critical not only for...

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Detalles Bibliográficos
Autores principales: Fujimori, Ko, Iguchi, Yusuke, Yamashita, Yukiko, Gohda, Keigo, Teno, Naoki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6891315/
https://www.ncbi.nlm.nih.gov/pubmed/31744088
http://dx.doi.org/10.3390/molecules24224155