Design, Synthesis and Preliminary Biological Evaluation of Benzylsulfone Coumarin Derivatives as Anti-Cancer Agents

In this work, a series of benzylsulfone coumarin derivatives 5a–5o were synthesized and characterized. Kinase inhibitory activity assay indicated that most of the compounds showed considerable activity against PI3K. Anti-tumor activity studies of the active compounds were also carried out in vitro o...

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Detalles Bibliográficos
Autores principales: Wang, Tao, Peng, Tao, Wen, Xiaoxue, Wang, Gang, Sun, Yunbo, Liu, Shuchen, Zhang, Shouguo, Wang, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6891324/
https://www.ncbi.nlm.nih.gov/pubmed/31703373
http://dx.doi.org/10.3390/molecules24224034

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6891324/
https://www.ncbi.nlm.nih.gov/pubmed/31703373
http://dx.doi.org/10.3390/molecules24224034

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