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Design, Synthesis and Biological Evaluation of Diosgenin-Amino Acid Derivatives with Dual Functions of Neuroprotection and Angiogenesis

Diosgenin, a natural product with steroidal structure, has a wide range of clinical applications in China. It also shows great potential in the treatment of blood clots and nerve damage. To enhance the bioavailability as well as efficacy of diosgenin, eighteen diosgenin-amino acid derivatives were d...

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Detalles Bibliográficos
Autores principales: Cai, Desheng, Qi, Jinchai, Yang, Yuqin, Zhang, Wenxi, Zhou, Fei, Jia, Xiaohui, Guo, Wenbo, Huang, Xuemei, Gao, Feng, Chen, Hongshan, Li, Tong, Li, Guoping, Wang, Penglong, Zhang, Yuzhong, Lei, Haimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6891328/
https://www.ncbi.nlm.nih.gov/pubmed/31703284
http://dx.doi.org/10.3390/molecules24224025