Synthesis and Anticancer Activity of CDDO and CDDO-Me, Two Derivatives of Natural Triterpenoids

Triterpenoids are natural compounds synthesized by plants through cyclization of squalene, known for their weak anti-inflammatory activity. 2-cyano-3,12-dioxooleana-1,9(11)-dien-28-oic acid (CDDO), and its C28 modified derivative, methyl-ester (CDDO-Me, also known as bardoxolone methyl), are two syn...

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Detalles Bibliográficos
Autores principales: Borella, Rebecca, Forti, Luca, Gibellini, Lara, De Gaetano, Anna, De Biasi, Sara, Nasi, Milena, Cossarizza, Andrea, Pinti, Marcello
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6891335/
https://www.ncbi.nlm.nih.gov/pubmed/31766211
http://dx.doi.org/10.3390/molecules24224097

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6891335/
https://www.ncbi.nlm.nih.gov/pubmed/31766211
http://dx.doi.org/10.3390/molecules24224097

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