Lunasin Improves the LDL-C Lowering Efficacy of Simvastatin via Inhibiting PCSK9 Expression in Hepatocytes and ApoE(−/−) Mice

Statins are the most popular therapeutic drugs to lower plasma low density lipoprotein cholesterol (LDL-C) synthesis by competitively inhibiting hydroxyl-3-methyl-glutaryl-CoA (HMG-CoA) reductase and up-regulating the hepatic low density lipoprotein receptor (LDLR). However, the concomitant up-regul...

Descripción completa

Detalles Bibliográficos
Autores principales: Gu, Lili, Gong, Yaqin, Zhao, Cheng, Wang, Yue, Tian, Qinghua, Lei, Gaoxin, Liang, Yalin, Zhao, Wenfeng, Tan, Shuhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6891362/
https://www.ncbi.nlm.nih.gov/pubmed/31731717
http://dx.doi.org/10.3390/molecules24224140

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6891362/
https://www.ncbi.nlm.nih.gov/pubmed/31731717
http://dx.doi.org/10.3390/molecules24224140

Ejemplares similares