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Investigation of the In-Vivo Cytotoxicity and the In Silico-Prediction of MDM2-p53 Inhibitor Potential of Euphorbia peplus Methanolic Extract in Rats

This study explored the probable in vivo cardiac and renal toxicities together with in silico approaches for predicting the apoptogenic potential of Euphorbia peplus methanolic extract (EPME) in rats. Cardiac and renal injury biomarkers were estimated with histopathological and immunohistochemical e...

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Detalles Bibliográficos
Autores principales: Abd-Elhakim, Yasmina M., Abdo Nassan, Mohamed, Salem, Gamal A., Sasi, Abdelkarim, Aldhahrani, Adil, Ben Issa, Khaled, Abdel-Rahman Mohamed, Amany
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6891376/
https://www.ncbi.nlm.nih.gov/pubmed/31689934
http://dx.doi.org/10.3390/toxins11110642