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Crosstalk between Human Microvascular Endothelial Cells and Tubular Epithelial Cells Modulates Pro-Inflammatory Responses Induced by Shiga Toxin Type 2 and Subtilase Cytotoxin

Hemolytic uremic syndrome (HUS) is a consequence of Shiga toxin (Stx)-producing Escherichia coli (STEC) infection and is the most frequent cause of acute renal failure (ARF) in children. Subtilase cytotoxin (SubAB) has also been associated with HUS pathogenesis. We previously reported that Stx2 and...

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Detalles Bibliográficos
Autores principales: Álvarez, Romina S., Jancic, Carolina, Garimano, Nicolás, Sacerdoti, Flavia, Paton, Adrienne W., Paton, James C., Ibarra, Cristina, Amaral, María M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6891416/
https://www.ncbi.nlm.nih.gov/pubmed/31703347
http://dx.doi.org/10.3390/toxins11110648