ENPP1, an Old Enzyme with New Functions, and Small Molecule Inhibitors—A STING in the Tale of ENPP1

Ectonucleotide pyrophosphatase/phosphodiesterase I (ENPP1) was identified several decades ago as a type II transmembrane glycoprotein with nucleotide pyrophosphatase and phosphodiesterase enzymatic activities, critical for purinergic signaling. Recently, ENPP1 has emerged as a critical phosphodieste...

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Detalles Bibliográficos
Autores principales: Onyedibe, Kenneth I., Wang, Modi, Sintim, Herman O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6891441/
https://www.ncbi.nlm.nih.gov/pubmed/31752288
http://dx.doi.org/10.3390/molecules24224192

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6891441/
https://www.ncbi.nlm.nih.gov/pubmed/31752288
http://dx.doi.org/10.3390/molecules24224192

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