Synthesis, Structure and In Vitro Cytotoxic Activity of Novel Cinchona—Chalcone Hybrids with 1,4-Disubstituted- and 1,5-Disubstituted 1,2,3-Triazole Linkers

By means of copper(I)-and ruthenium(II)-catalyzed click reactions of quinine- and quinidine-derived alkynes with azide-substituted chalcones a systematic series of novel cinchona-chalcone hybrid compounds, containing 1,4-disubstituted- and 1,5-disubstituted 1,2,3-triazole linkers, were synthesized a...

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Detalles Bibliográficos
Autores principales: Jernei, Tamás, Duró, Cintia, Dembo, Antonio, Lajkó, Eszter, Takács, Angéla, Kőhidai, László, Schlosser, Gitta, Csámpai, Antal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6891474/
https://www.ncbi.nlm.nih.gov/pubmed/31718009
http://dx.doi.org/10.3390/molecules24224077

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6891474/
https://www.ncbi.nlm.nih.gov/pubmed/31718009
http://dx.doi.org/10.3390/molecules24224077

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