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Synthesis, Structure and In Vitro Cytotoxic Activity of Novel Cinchona—Chalcone Hybrids with 1,4-Disubstituted- and 1,5-Disubstituted 1,2,3-Triazole Linkers
By means of copper(I)-and ruthenium(II)-catalyzed click reactions of quinine- and quinidine-derived alkynes with azide-substituted chalcones a systematic series of novel cinchona-chalcone hybrid compounds, containing 1,4-disubstituted- and 1,5-disubstituted 1,2,3-triazole linkers, were synthesized a...
Autores principales: | Jernei, Tamás, Duró, Cintia, Dembo, Antonio, Lajkó, Eszter, Takács, Angéla, Kőhidai, László, Schlosser, Gitta, Csámpai, Antal |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6891474/ https://www.ncbi.nlm.nih.gov/pubmed/31718009 http://dx.doi.org/10.3390/molecules24224077 |
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