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Spider Knottin Pharmacology at Voltage-Gated Sodium Channels and Their Potential to Modulate Pain Pathways
Voltage-gated sodium channels (Na(V)s) are a key determinant of neuronal signalling. Neurotoxins from diverse taxa that selectively activate or inhibit Na(V) channels have helped unravel the role of Na(V) channels in diseases, including chronic pain. Spider venoms contain the most diverse array of i...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2019
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6891507/ https://www.ncbi.nlm.nih.gov/pubmed/31671792 http://dx.doi.org/10.3390/toxins11110626 |