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The Development of Novel Compounds Against Malaria: Quinolines, Triazolpyridines, Pyrazolopyridines and Pyrazolopyrimidines

Based on medicinal chemistry tools, new compounds for malaria treatment were designed. The scaffolds of the drugs used to treat malaria, such as chloroquine, primaquine, amodiaquine, mefloquine and sulfadoxine, were used as inspiration. We demonstrated the importance of quinoline and non-quinoline d...

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Detalles Bibliográficos
Autores principales: C. S. Pinheiro, Luiz, M. Feitosa, Lívia, O. Gandi, Marilia, F. Silveira, Flávia, Boechat, Nubia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6891514/
https://www.ncbi.nlm.nih.gov/pubmed/31766184
http://dx.doi.org/10.3390/molecules24224095