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The Development of Novel Compounds Against Malaria: Quinolines, Triazolpyridines, Pyrazolopyridines and Pyrazolopyrimidines
Based on medicinal chemistry tools, new compounds for malaria treatment were designed. The scaffolds of the drugs used to treat malaria, such as chloroquine, primaquine, amodiaquine, mefloquine and sulfadoxine, were used as inspiration. We demonstrated the importance of quinoline and non-quinoline d...
Autores principales: | C. S. Pinheiro, Luiz, M. Feitosa, Lívia, O. Gandi, Marilia, F. Silveira, Flávia, Boechat, Nubia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6891514/ https://www.ncbi.nlm.nih.gov/pubmed/31766184 http://dx.doi.org/10.3390/molecules24224095 |
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