South African Abietane Diterpenoids and Their Analogs as Potential Antimalarials: Novel Insights from Hybrid Computational Approaches

The hemoglobin degradation process in Plasmodium parasites is vital for nutrient acquisition required for their growth and proliferation. In P. falciparum, falcipains (FP-2 and FP-3) are the major hemoglobinases, and remain attractive antimalarial drug targets. Other Plasmodium species also possess...

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Detalles Bibliográficos
Autores principales: Musyoka, Thommas, Bishop, Özlem Tastan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6891524/
https://www.ncbi.nlm.nih.gov/pubmed/31703388
http://dx.doi.org/10.3390/molecules24224036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6891524/
https://www.ncbi.nlm.nih.gov/pubmed/31703388
http://dx.doi.org/10.3390/molecules24224036

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