Identifying Promiscuous Compounds with Activity against Different Target Classes

Compounds with multitarget activity are of high interest for polypharmacological drug discovery. Such promiscuous compounds might be active against closely related target proteins from the same family or against distantly related or unrelated targets. Compounds with activity against distinct targets...

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Detalles Bibliográficos
Autores principales: Feldmann, Christian, Miljković, Filip, Yonchev, Dimitar, Bajorath, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6891533/
https://www.ncbi.nlm.nih.gov/pubmed/31752252
http://dx.doi.org/10.3390/molecules24224185

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6891533/
https://www.ncbi.nlm.nih.gov/pubmed/31752252
http://dx.doi.org/10.3390/molecules24224185

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