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Identifying Promiscuous Compounds with Activity against Different Target Classes
Compounds with multitarget activity are of high interest for polypharmacological drug discovery. Such promiscuous compounds might be active against closely related target proteins from the same family or against distantly related or unrelated targets. Compounds with activity against distinct targets...
Autores principales: | Feldmann, Christian, Miljković, Filip, Yonchev, Dimitar, Bajorath, Jürgen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6891533/ https://www.ncbi.nlm.nih.gov/pubmed/31752252 http://dx.doi.org/10.3390/molecules24224185 |
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