Cargando…

Curcumin Nicotinate Selectively Induces Cancer Cell Apoptosis and Cycle Arrest through a P53-Mediated Mechanism

Curcumin is an anticancer agent, but adverse effects and low bioavailability are its main drawbacks, which drives efforts in chemical modifications of curcumin. This study evaluated antiproliferative activity and cancer cell selectivity of a curcumin derivative, curcumin nicotinate (CN), in which tw...

Descripción completa

Detalles Bibliográficos
Autores principales: He, Ying-chun, He, Lan, Khoshaba, Ramina, Lu, Fang-guo, Cai, Chuan, Zhou, Fang-liang, Liao, Duan-fang, Cao, Deliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6891632/
https://www.ncbi.nlm.nih.gov/pubmed/31752145
http://dx.doi.org/10.3390/molecules24224179