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Curcumin Nicotinate Selectively Induces Cancer Cell Apoptosis and Cycle Arrest through a P53-Mediated Mechanism
Curcumin is an anticancer agent, but adverse effects and low bioavailability are its main drawbacks, which drives efforts in chemical modifications of curcumin. This study evaluated antiproliferative activity and cancer cell selectivity of a curcumin derivative, curcumin nicotinate (CN), in which tw...
Autores principales: | He, Ying-chun, He, Lan, Khoshaba, Ramina, Lu, Fang-guo, Cai, Chuan, Zhou, Fang-liang, Liao, Duan-fang, Cao, Deliang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6891632/ https://www.ncbi.nlm.nih.gov/pubmed/31752145 http://dx.doi.org/10.3390/molecules24224179 |
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