Zebrafish-Based Discovery of Antiseizure Compounds from the North Sea: Isoquinoline Alkaloids TMC-120A and TMC-120B

There is a high need for the development of new and improved antiseizure drugs (ASDs) to treat epilepsy. Despite the potential of marine natural products (MNPs), the EU marine biodiscovery consortium PharmaSea has made the only effort to date to perform ASD discovery based on large-scale screening o...

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Detalles Bibliográficos
Autores principales: Copmans, Daniëlle, Kildgaard, Sara, Rasmussen, Silas A., Ślęzak, Monika, Dirkx, Nina, Partoens, Michèle, Esguerra, Camila V., Crawford, Alexander D., Larsen, Thomas O., de Witte, Peter A. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6891649/
https://www.ncbi.nlm.nih.gov/pubmed/31731399
http://dx.doi.org/10.3390/md17110607

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6891649/
https://www.ncbi.nlm.nih.gov/pubmed/31731399
http://dx.doi.org/10.3390/md17110607

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