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Novel Microcystins from Planktothrix prolifica NIVA-CYA 544 Identified by LC-MS/MS, Functional Group Derivatization and (15)N-labeling

Microcystins are cyclic heptapeptides from cyanobacteria that are potent inhibitors of protein phosphatases and are toxic to animals and humans. At present, more than 250 microcystin variants are known, with variants reported for all seven peptide moieties. While d-glutamic acid (d-Glu) is highly-co...

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Detalles Bibliográficos
Autores principales: Mallia, Vittoria, Uhlig, Silvio, Rafuse, Cheryl, Meija, Juris, Miles, Christopher O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6891653/
https://www.ncbi.nlm.nih.gov/pubmed/31731697
http://dx.doi.org/10.3390/md17110643