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Structural Analysis, Molecular Modelling and Preliminary Competition Binding Studies of AM-DAN as a NMDA Receptor PCP-Site Fluorescent Ligand

Excitotoxicity related to the dysfunction of the N-methyl-d-aspartate receptor (NMDAR) has been indicated to play an integral role in the pathophysiology of multiple disease states, including neurodegenerative disorders such as Parkinson’s disease. There is a notable gap in the market for novel NMDA...

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Detalles Bibliográficos
Autores principales: Ndzibongwana, Sethu, Ngobese, Samukelo, Sayed, Ahmad, Shongwe, Ciniso, White-Phillips, Simon, Joubert, Jacques
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6891720/
https://www.ncbi.nlm.nih.gov/pubmed/31766120
http://dx.doi.org/10.3390/molecules24224092