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Structural Analysis, Molecular Modelling and Preliminary Competition Binding Studies of AM-DAN as a NMDA Receptor PCP-Site Fluorescent Ligand
Excitotoxicity related to the dysfunction of the N-methyl-d-aspartate receptor (NMDAR) has been indicated to play an integral role in the pathophysiology of multiple disease states, including neurodegenerative disorders such as Parkinson’s disease. There is a notable gap in the market for novel NMDA...
Autores principales: | Ndzibongwana, Sethu, Ngobese, Samukelo, Sayed, Ahmad, Shongwe, Ciniso, White-Phillips, Simon, Joubert, Jacques |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6891720/ https://www.ncbi.nlm.nih.gov/pubmed/31766120 http://dx.doi.org/10.3390/molecules24224092 |
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