Dialkylation of Indoles with Trichloroacetimidates to Access 3,3-Disubstituted Indolenines

2-Substituted indoles may be directly transformed to 3,3-dialkyl indolenines with trichloroacetimidate electrophiles and the Lewis acid TMSOTf. These reactions provide rapid access to complex indolenines which are present in a variety of complex natural products and medicinally relevant small molecu...

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Detalles Bibliográficos
Autores principales: Suzuki, Tamie, Mate, Nilamber A., Adhikari, Arijit A., Chisholm, John D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6891773/
https://www.ncbi.nlm.nih.gov/pubmed/31731742
http://dx.doi.org/10.3390/molecules24224143

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6891773/
https://www.ncbi.nlm.nih.gov/pubmed/31731742
http://dx.doi.org/10.3390/molecules24224143

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