Electrostatically Driven Guanidinium Interaction Domains that Control Hydrogel-Mediated Protein Delivery In Vivo

[Image: see text] Protein biologics are an important class of drugs, but the necessity for frequent parenteral administration is a major limitation. Drug-delivery materials offer a potential solution, but protein-material adsorption can cause denaturation, which reduces their effectiveness. Here, we...

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Detalles Bibliográficos
Autores principales: Miller, Stephen E., Yamada, Yuji, Patel, Nimit, Suárez, Ernesto, Andrews, Caroline, Tau, Steven, Luke, Brian T., Cachau, Raul E., Schneider, Joel P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6891851/
https://www.ncbi.nlm.nih.gov/pubmed/31807676
http://dx.doi.org/10.1021/acscentsci.9b00501

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6891851/
https://www.ncbi.nlm.nih.gov/pubmed/31807676
http://dx.doi.org/10.1021/acscentsci.9b00501

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