Site-Selective C–H Halogenation Using Flavin-Dependent Halogenases Identified via Family-Wide Activity Profiling

[Image: see text] Enzymes are powerful catalysts for site-selective C–H bond functionalization. Identifying suitable enzymes for this task and for biocatalysis in general remains challenging, however, due to the fundamental difficulty of predicting catalytic activity from sequence information. In th...

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Detalles Bibliográficos
Autores principales: Fisher, Brian F., Snodgrass, Harrison M., Jones, Krysten A., Andorfer, Mary C., Lewis, Jared C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6891866/
https://www.ncbi.nlm.nih.gov/pubmed/31807686
http://dx.doi.org/10.1021/acscentsci.9b00835

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6891866/
https://www.ncbi.nlm.nih.gov/pubmed/31807686
http://dx.doi.org/10.1021/acscentsci.9b00835

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