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DNA‐Encoded Libraries: Aryl Fluorosulfonates as Versatile Electrophiles Enabling Facile On‐DNA Suzuki, Sonogashira, and Buchwald Reactions

Using (hetero)aryl fluorosulfonates as versatile electrophiles, facile on‐DNA cross‐coupling reactions of Suzuki, Sonogashira, and Buchwald are reported here. Notably, all of these reactions show excellent functional group tolerance, mild reaction conditions (relative low temperature and open to air...

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Detalles Bibliográficos
Autores principales: Xu, Hongtao, Ma, Fei, Wang, Nan, Hou, Wei, Xiong, Huan, Lu, Fengping, Li, Jie, Wang, Shuyue, Ma, Peixiang, Yang, Guang, Lerner, Richard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6891896/
https://www.ncbi.nlm.nih.gov/pubmed/31832315
http://dx.doi.org/10.1002/advs.201901551