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GLTSCR1 Negatively Regulates BRD4‐Dependent Transcription Elongation and Inhibits CRC Metastasis

Frameshift mutations frequently occur in colorectal cancer (CRC) with microsatellite instability (MSI), but the nature and biological function of many MSI‐associated mutations remain elusive. Here, an MSI frameshift mutation is identified in glioma tumor suppressor candidate region gene 1 (GLTSCR1)...

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Detalles Bibliográficos
Autores principales: Han, Fengyan, Zhang, Lei, Chen, Chaoyi, Wang, Yan, Zhang, Yi, Qian, Lili, Sun, Wenjie, Zhou, Dan, Yang, Beibei, Zhang, Honghe, Lai, Maode
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6891902/
https://www.ncbi.nlm.nih.gov/pubmed/31832310
http://dx.doi.org/10.1002/advs.201901114