Tumor suppressor HIC1 is synergistically compromised by cancer-associated fibroblasts and tumor cells through the IL-6/pSTAT3 axis in breast cancer

BACKGROUND: Interleukin-6 (IL-6) is commonly highly secreted in the breast cancer (BrCA) microenvironment and implicated in disease development. In this study, we aimed to determine the role of the IL-6/pSTAT3/HIC1 axis in the breast cancer microenvironment, including in cancer-associated fibroblast...

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Detalles Bibliográficos
Autores principales: Sun, Xueqing, Qu, Qing, Lao, Yimin, Zhang, Mi, Yin, Xiaoling, Zhu, Huiqin, Wang, Ying, Yang, Jie, Yi, Jing, Hao, Mingang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6891969/
https://www.ncbi.nlm.nih.gov/pubmed/31795965
http://dx.doi.org/10.1186/s12885-019-6333-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6891969/
https://www.ncbi.nlm.nih.gov/pubmed/31795965
http://dx.doi.org/10.1186/s12885-019-6333-6

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