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Afann: bias adjustment for alignment-free sequence comparison based on sequencing data using neural network regression
Alignment-free methods, more time and memory efficient than alignment-based methods, have been widely used for comparing genome sequences or raw sequencing samples without assembly. However, in this study, we show that alignment-free dissimilarity calculated based on sequencing samples can be overes...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6891986/ https://www.ncbi.nlm.nih.gov/pubmed/31801606 http://dx.doi.org/10.1186/s13059-019-1872-3 |