Dimerization of MORC2 through its C-terminal coiled-coil domain enhances chromatin dynamics and promotes DNA repair

Decondesation of the highly compacted chromatin architecture is essential for efficient DNA repair, but how this is achieved remains largely unknown. Here, we report that microrchidia family CW-type zinc finger protein 2 (MORC2), a newly identified ATPase-dependent chromatin remodeling enzyme, is re...

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Detalles Bibliográficos
Autores principales: Xie, Hong-Yan, Zhang, Tai-Mei, Hu, Shu-Yuan, Shao, Zhi-Ming, Li, Da-Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6892150/
https://www.ncbi.nlm.nih.gov/pubmed/31796101
http://dx.doi.org/10.1186/s12964-019-0477-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6892150/
https://www.ncbi.nlm.nih.gov/pubmed/31796101
http://dx.doi.org/10.1186/s12964-019-0477-5

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