The notch target gene HEYL modulates metastasis forming capacity of colorectal cancer patient-derived spheroid cells in vivo

BACKGROUND: While colorectal cancer (CRC) patients with localized disease have a favorable prognosis, the five-year-survival rate in patients with distant spread is still below 15%. Hence, a detailed understanding of the mechanisms regulating metastasis formation is essential to develop therapeutic...

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Detalles Bibliográficos
Autores principales: Weber, Sarah, Koschade, Sebastian E., Hoffmann, Christopher M., Dubash, Taronish D., Giessler, Klara M., Dieter, Sebastian M., Herbst, Friederike, Glimm, Hanno, Ball, Claudia R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6892194/
https://www.ncbi.nlm.nih.gov/pubmed/31796022
http://dx.doi.org/10.1186/s12885-019-6396-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6892194/
https://www.ncbi.nlm.nih.gov/pubmed/31796022
http://dx.doi.org/10.1186/s12885-019-6396-4

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