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Genetics and functions of the retinoic acid pathway, with special emphasis on the eye

Retinoic acid (RA) is a potent morphogen required for embryonic development. RA is formed in a multistep process from vitamin A (retinol); RA acts in a paracrine fashion to shape the developing eye and is essential for normal optic vesicle and anterior segment formation. Perturbation in RA-signaling...

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Detalles Bibliográficos
Autores principales: Thompson, Brian, Katsanis, Nicholas, Apostolopoulos, Nicholas, Thompson, David C., Nebert, Daniel W., Vasiliou, Vasilis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6892198/
https://www.ncbi.nlm.nih.gov/pubmed/31796115
http://dx.doi.org/10.1186/s40246-019-0248-9