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Genetics and functions of the retinoic acid pathway, with special emphasis on the eye
Retinoic acid (RA) is a potent morphogen required for embryonic development. RA is formed in a multistep process from vitamin A (retinol); RA acts in a paracrine fashion to shape the developing eye and is essential for normal optic vesicle and anterior segment formation. Perturbation in RA-signaling...
Autores principales: | Thompson, Brian, Katsanis, Nicholas, Apostolopoulos, Nicholas, Thompson, David C., Nebert, Daniel W., Vasiliou, Vasilis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6892198/ https://www.ncbi.nlm.nih.gov/pubmed/31796115 http://dx.doi.org/10.1186/s40246-019-0248-9 |
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