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Causal association of type 2 diabetes with amyotrophic lateral sclerosis: new evidence from Mendelian randomization using GWAS summary statistics

BACKGROUND: Associations between type 2 diabetes (T2D) and amyotrophic lateral sclerosis (ALS) were discovered in observational studies in both European and East Asian populations. However, whether such associations are causal remains largely unknown. METHODS: We employed a two-sample Mendelian rand...

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Detalles Bibliográficos
Autores principales: Zeng, Ping, Wang, Ting, Zheng, Junnian, Zhou, Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6892209/
https://www.ncbi.nlm.nih.gov/pubmed/31796040
http://dx.doi.org/10.1186/s12916-019-1448-9