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Silencing of microRNA-146a alleviates the neural damage in temporal lobe epilepsy by down-regulating Notch-1

This study aimed to evaluate the specific regulatory roles of microRNA-146a (miRNA-146a) in temporal lobe epilepsy (TLE) and explore the related regulatory mechanisms. A rat model of TLE was established by intraperitoneal injection of lithium chloride-pilocarpine. These model rats were injected intr...

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Detalles Bibliográficos
Autores principales: Huang, Hui, Cui, Guiyun, Tang, Hai, Kong, Lingwen, Wang, Xiaopeng, Cui, Chenchen, Xiao, Qihua, Ji, Huiming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6892218/
https://www.ncbi.nlm.nih.gov/pubmed/31796120
http://dx.doi.org/10.1186/s13041-019-0523-7