KCC2 expression levels are reduced in post mortem brain tissue of Rett syndrome patients

Rett Syndrome (RTT) is a neurodevelopmental disorder caused by mutations in the Methyl CpG binding protein 2 (MECP2) gene. Deficient K(+)-Cl(—)co-transporter 2 (KCC2) expression is suggested to play a key role in the neurodevelopmental delay in RTT patients’ neuronal networks. KCC2 is a major player...

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Detalles Bibliográficos
Autores principales: Hinz, Lisa, Torrella Barrufet, Joan, Heine, Vivi M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6892240/
https://www.ncbi.nlm.nih.gov/pubmed/31796123
http://dx.doi.org/10.1186/s40478-019-0852-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6892240/
https://www.ncbi.nlm.nih.gov/pubmed/31796123
http://dx.doi.org/10.1186/s40478-019-0852-x

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