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Dual CCR5/CCR2 targeting: opportunities for the cure of complex disorders
The chemokine system mediates acute inflammation by driving leukocyte migration to damaged or infected tissues. However, elevated expression of chemokines and their receptors can contribute to chronic inflammation and malignancy. Thus, great effort has been taken to target these molecules. The first...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6892368/ https://www.ncbi.nlm.nih.gov/pubmed/31377844 http://dx.doi.org/10.1007/s00018-019-03255-6 |