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Dual CCR5/CCR2 targeting: opportunities for the cure of complex disorders

The chemokine system mediates acute inflammation by driving leukocyte migration to damaged or infected tissues. However, elevated expression of chemokines and their receptors can contribute to chronic inflammation and malignancy. Thus, great effort has been taken to target these molecules. The first...

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Detalles Bibliográficos
Autores principales: Fantuzzi, Laura, Tagliamonte, Maria, Gauzzi, Maria Cristina, Lopalco, Lucia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6892368/
https://www.ncbi.nlm.nih.gov/pubmed/31377844
http://dx.doi.org/10.1007/s00018-019-03255-6