Structure and Function of Cochlear Gap Junctions and Implications for the Translation of Cochlear Gene Therapies

Connexins (Cxs) are ubiquitous membrane proteins that are found throughout vertebrate organs, acting as building blocks of the gap junctions (GJs) known to play vital roles in the normal function of many organs. Mutations in Cx genes (particularly GJB2, which encodes Cx26) cause approximately half o...

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Detalles Bibliográficos
Autores principales: Wu, Xuewen, Zhang, Wenjuan, Li, Yihui, Lin, Xi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Cellular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6892400/
https://www.ncbi.nlm.nih.gov/pubmed/31827424
http://dx.doi.org/10.3389/fncel.2019.00529

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6892400/
https://www.ncbi.nlm.nih.gov/pubmed/31827424
http://dx.doi.org/10.3389/fncel.2019.00529

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