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Structure and Function of Cochlear Gap Junctions and Implications for the Translation of Cochlear Gene Therapies
Connexins (Cxs) are ubiquitous membrane proteins that are found throughout vertebrate organs, acting as building blocks of the gap junctions (GJs) known to play vital roles in the normal function of many organs. Mutations in Cx genes (particularly GJB2, which encodes Cx26) cause approximately half o...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6892400/ https://www.ncbi.nlm.nih.gov/pubmed/31827424 http://dx.doi.org/10.3389/fncel.2019.00529 |