Phenotypic proteomic profiling identifies a landscape of targets for circadian clock–modulating compounds

Determining the exact targets and mechanisms of action of drug molecules that modulate circadian rhythms is critical to develop novel compounds to treat clock-related disorders. Here, we have used phenotypic proteomic profiling (PPP) to systematically determine molecular targets of four circadian pe...

Descripción completa

Detalles Bibliográficos
Autores principales: Ray, Sandipan, Lach, Radoslaw, Heesom, Kate J, Valekunja, Utham K, Encheva, Vesela, Snijders, Ambrosius P, Reddy, Akhilesh B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2019
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6892409/
https://www.ncbi.nlm.nih.gov/pubmed/31792063
http://dx.doi.org/10.26508/lsa.201900603

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6892409/
https://www.ncbi.nlm.nih.gov/pubmed/31792063
http://dx.doi.org/10.26508/lsa.201900603

Ejemplares similares