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ADAP1 promotes invasive squamous cell carcinoma progression and predicts patient survival

Invasive squamous cell carcinoma (SCC) is aggressive cancer with a high risk of recurrence and metastasis, but the critical determinants of its progression remain elusive. Here, we identify ADAP1, a GTPase-activating protein (GAP) for ARF6 up-regulated in TGF-β-responding invasive tumor cells, as a...

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Detalles Bibliográficos
Autores principales: Van Duzer, Avery, Taniguchi, Sachiko, Elhance, Ajit, Tsujikawa, Takahiro, Oshimori, Naoki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6892435/
https://www.ncbi.nlm.nih.gov/pubmed/31792062
http://dx.doi.org/10.26508/lsa.201900582